In vitro and in vivo genotoxicity of 1,3-butadiene and metabolites.
1,3-Butadiene and two major genotoxic metabolites 3,4-epoxybutene (EB) and 1,2:3,4-diepoxybutane (DEB) were used as model compounds to determine if genetic toxicity findings in animal and human cells can aid in extrapolating animal toxicity data to man. Sister chromatid exchange (SCE) and micronucle...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1990
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567734/ |