Serine and glycine metabolism in cancer☆
•Serine and glycine are essential metabolites for cancer cells.•Serine and glycine provide precursors for macromolecules and antioxidant defence.•Metabolic enzymes of serine and glycine biosynthesis are upregulated in cancer.•Innovative anticancer therapy is aiming to target serine and glycine biosy...
Main Authors: | Amelio, Ivano, Cutruzzolá, Francesca, Antonov, Alexey, Agostini, Massimiliano, Melino, Gerry |
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Format: | Online |
Language: | English |
Published: |
Elsevier Trends Journals
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989988/ |
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