Serine and glycine metabolism in cancer☆

Serine and glycine metabolism in cancer☆

•Serine and glycine are essential metabolites for cancer cells.•Serine and glycine provide precursors for macromolecules and antioxidant defence.•Metabolic enzymes of serine and glycine biosynthesis are upregulated in cancer.•Innovative anticancer therapy is aiming to target serine and glycine biosy...

Full description

Bibliographic Details
Main Authors: Amelio, Ivano, Cutruzzolá, Francesca, Antonov, Alexey, Agostini, Massimiliano, Melino, Gerry
Format: Online
Language:English
Published: Elsevier Trends Journals 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989988/
id pubmed-3989988
recordtype oai_dc
spelling pubmed-39899882014-04-17 Serine and glycine metabolism in cancer☆ Amelio, Ivano Cutruzzolá, Francesca Antonov, Alexey Agostini, Massimiliano Melino, Gerry Review •Serine and glycine are essential metabolites for cancer cells.•Serine and glycine provide precursors for macromolecules and antioxidant defence.•Metabolic enzymes of serine and glycine biosynthesis are upregulated in cancer.•Innovative anticancer therapy is aiming to target serine and glycine biosynthesis. Elsevier Trends Journals 2014-04 /pmc/articles/PMC3989988/ /pubmed/24657017 http://dx.doi.org/10.1016/j.tibs.2014.02.004 Text en Crown Copyright © 2014 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Amelio, Ivano
Cutruzzolá, Francesca
Antonov, Alexey
Agostini, Massimiliano
Melino, Gerry
spellingShingle Amelio, Ivano
Cutruzzolá, Francesca
Antonov, Alexey
Agostini, Massimiliano
Melino, Gerry
Serine and glycine metabolism in cancer☆
author_facet Amelio, Ivano
Cutruzzolá, Francesca
Antonov, Alexey
Agostini, Massimiliano
Melino, Gerry
author_sort Amelio, Ivano
title Serine and glycine metabolism in cancer☆
title_short Serine and glycine metabolism in cancer☆
title_full Serine and glycine metabolism in cancer☆
title_fullStr Serine and glycine metabolism in cancer☆
title_full_unstemmed Serine and glycine metabolism in cancer☆
title_sort serine and glycine metabolism in cancer☆
description •Serine and glycine are essential metabolites for cancer cells.•Serine and glycine provide precursors for macromolecules and antioxidant defence.•Metabolic enzymes of serine and glycine biosynthesis are upregulated in cancer.•Innovative anticancer therapy is aiming to target serine and glycine biosynthesis.
publisher Elsevier Trends Journals
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989988/
_version_ 1612079174756859904

Similar Items