Serine and glycine metabolism in cancer☆

•Serine and glycine are essential metabolites for cancer cells.•Serine and glycine provide precursors for macromolecules and antioxidant defence.•Metabolic enzymes of serine and glycine biosynthesis are upregulated in cancer.•Innovative anticancer therapy is aiming to target serine and glycine biosy...

Full description

Bibliographic Details
Main Authors: Amelio, Ivano, Cutruzzolá, Francesca, Antonov, Alexey, Agostini, Massimiliano, Melino, Gerry
Format: Online
Language:English
Published: Elsevier Trends Journals 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989988/