TAp73 promotes anti-senescence-anabolism not proliferation
TAp73, a member of the p53 family, has been traditionally considered a tumor suppressor gene, but a recent report has claimed that it can promote cellular proliferation. This assumption is based on biochemical evidence of activation of anabolic metabolism, with enhanced pentose phosphate shunt (PPP)...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276786/ |