Structure of the SecY channel during initiation of protein translocation

Structure of the SecY channel during initiation of protein translocation

Many secretory proteins are targeted by signal sequences to a protein-conducting channel, formed by prokaryotic SecY- or eukaryotic Sec61-complexes, and are translocated across the membrane during their synthesis1,2. Crystal structures of the inactive channel show that the SecY subunit of the hetero...

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Bibliographic Details
Main Authors:	Park, Eunyong, Ménétret, Jean-François, Gumbart, James C., Ludtke, Steven J., Li, Weikai, Whynot, Andrew, Rapoport, Tom A., Akey, Christopher W.
Format:	Online
Language:	English
Published:	2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948209/

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