SecY alterations that impair membrane protein folding and generate a membrane stress
We report on a class of Escherichia coli SecY mutants that impair membrane protein folding. The mutants also up-regulate the Cpx/σE stress response pathways. Similar stress induction was also observed in response to a YidC defect in membrane protein biogenesis but not in response to the signal recog...
| Main Authors: | , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2007
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063957/ |