A role for the two-helix finger of the SecA ATPase in protein translocation

An important step in the biosynthesis of many proteins is their partial or complete translocation across the plasma membrane in prokaryotes or the endoplasmic reticulum membrane in eukaryotes 1. In bacteria, secretory proteins are generally translocated after completion of their synthesis by the int...

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Bibliographic Details
Main Authors: Erlandson, Karl J., Miller, Stephanie B. M., Nam, Yunsun, Osborne, Andrew R., Zimmer, Jochen, Rapoport, Tom A.
Format: Online
Language:English
Published: 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354775/