Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains

Calorie restriction (CR) has long been used to study lifespan effects and oppose the development of a broad array of age-related biological and pathological changes (increase healthspan). Yet, a comprehensive comparison of the metabolic phenotype across different genetic backgrounds to identify comm...

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Bibliographic Details
Main Authors: Collino, Sebastiano, Martin, François-Pierre J., Montoliu, Ivan, Barger, Jamie L., Da Silva, Laeticia, Prolla, Tomas A., Weindruch, Richard, Kochhar, Sunil
Format: Online
Language:English
Published: MDPI 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937836/