Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Recent observations suggest a lower incidence of malignancies in patients infected with HIV during treatment with Highly Active Anti-Retroviral Therapy (HAART) utilizing protease inhibitors. We investigated the effects of ritonavir, a FDA approved HIV protease inhibitor, on proliferation of pancreat...

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Bibliographic Details
Main Authors: Batchu, Ramesh B., Gruzdyn, Oksana V., Bryant, Christopher S., Qazi, Aamer M., Kumar, Sanjeev, Chamala, Sreedhar, Kung, Shu T., Sanka, Ramana S., Puttagunta, Udaya S., Weaver, Donald W., Gruber, Scott A.
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915194/

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