Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy
Pregnant women are usually excluded from clinical trials. Physiologically based pharmacokinetic (PBPK) modelling may provide a method to predict pharmacokinetics in pregnant women, without the need to perform extensive in vivo clinical trials. Here, we used mechanistic modelling to delineate the pot...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer International Publishing
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761019/ |