Effects of Tipranavir, Darunavir, and Ritonavir on Platelet Function, Coagulation, and Fibrinolysis in Healthy Volunteers

The use of HIV protease inhibitors (PIs) as part of antiretroviral therapy in the treatment of HIV-1 infection may be associated with an increased risk of bleeding. This prospective, randomized, open-label trial in healthy volunteers compared the effects of tipranavir/ritonavir (TPV/r), darunavir/ri...

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Bibliographic Details
Main Authors: Kort, Jens J, Aslanyan, Stella, Scherer, Joseph, Sabo, John P, Kohlbrenner, Veronika, Robinson, Patrick
Format: Online
Language:English
Published: Bentham Science Publishers Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343416/