NMDA receptor activation requires remodeling of inter-subunit contacts within ligand-binding heterodimers
Two classes of glutamate-activated channels mediate excitation at central synapses: N-methyl-d-aspartic acid (NMDA) receptors and non-NMDA receptors. Despite substantial structural homology, each class generates signals with characteristic kinetics and mediates distinct synaptic functions. In non-NM...
Main Authors: | Borschel, William F, Murthy, Swetha E, Kasperek, Eileen M, Popescu, Gabriela K |
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Format: | Online |
Language: | English |
Published: |
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899702/ |
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