NMDA receptor activation requires remodeling of inter-subunit contacts within ligand-binding heterodimers
Two classes of glutamate-activated channels mediate excitation at central synapses: N-methyl-d-aspartic acid (NMDA) receptors and non-NMDA receptors. Despite substantial structural homology, each class generates signals with characteristic kinetics and mediates distinct synaptic functions. In non-NM...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899702/ |