Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma
Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored as anti-cancer agents. In fact, two histone deacetylase inhibitors (HDIs), SA...
Main Authors: | Wells, Christina E., Bhaskara, Srividya, Stengel, Kristy R., Zhao, Yue, Sirbu, Bianca, Chagot, Benjamin, Cortez, David, Khabele, Dineo, Chazin, Walter J., Cooper, Andrew, Jacques, Vincent, Rusche, James, Eischen, Christine M., McGirt, Laura Y., Hiebert, Scott W. |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718806/ |
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