Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma

Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma

Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored as anti-cancer agents. In fact, two histone deacetylase inhibitors (HDIs), SA...

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Bibliographic Details
Main Authors: Wells, Christina E., Bhaskara, Srividya, Stengel, Kristy R., Zhao, Yue, Sirbu, Bianca, Chagot, Benjamin, Cortez, David, Khabele, Dineo, Chazin, Walter J., Cooper, Andrew, Jacques, Vincent, Rusche, James, Eischen, Christine M., McGirt, Laura Y., Hiebert, Scott W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718806/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718806/

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