The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
Epithelial ovarian cancer remains the deadliest gynecologic malignancy. Despite advances in treatment, new approaches are needed. Histone deacetylases (HDACs) are a family of enzymes that regulate gene expression by removing acetyl groups from lysine residues on histones and non-histone proteins. In...
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Format: | Online |
Language: | English |
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Frontiers Media S.A.
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033132/ |