Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides

Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides

B13 is a ceramide analogue and apoptosis inducer with potent cytotoxic activity. A series of arylpropyl sulfonamide analogues of B13 were evaluated for their cytotoxicity using MTT assays in prostate cancer PC-3 and leukemia HL-60 cell lines. Some compounds (4, 9, 13, 14, 15, and 20) showed stronger...

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Bibliographic Details
Main Authors:	Hwang, Yu Jin, Park, Sang Min, Yim, Chul Bu, Im, Chaeuk
Format:	Online
Language:	English
Published:	The Korean Physiological Society and The Korean Society of Pharmacology 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682085/

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