Cytotoxic Activity and Quantitative Structure Activity Relationships of Arylpropyl Sulfonamides
B13 is a ceramide analogue and apoptosis inducer with potent cytotoxic activity. A series of arylpropyl sulfonamide analogues of B13 were evaluated for their cytotoxicity using MTT assays in prostate cancer PC-3 and leukemia HL-60 cell lines. Some compounds (4, 9, 13, 14, 15, and 20) showed stronger...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Physiological Society and The Korean Society of Pharmacology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682085/ |