Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

The cross-recognition of peptides by cytotoxic T lymphocytes is a key element in immunology and in particular in peptide based immunotherapy. Here we develop three-dimensional (3D) quantitative structure-activity relationships (QSARs) to predict cross-recognition by Melan-A-specific cytotoxic T lymp...

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Bibliographic Details
Main Authors: Fagerberg, Theres, Zoete, Vincent, Viatte, Sebastien, Baumgaertner, Petra, Alves, Pedro M., Romero, Pedro, Speiser, Daniel E., Michielin, Olivier
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713012/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713012/

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