Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells
B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B13, since they are made by bioisosterically substituting the...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Korean Physiological Society and The Korean Society of Pharmacology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282231/ |