EMu: probabilistic inference of mutational processes and their localization in the cancer genome
The spectrum of mutations discovered in cancer genomes can be explained by the activity of a few elementary mutational processes. We present a novel probabilistic method, EMu, to infer the mutational signatures of these processes from a collection of sequenced tumors. EMu naturally incorporates the...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663107/ |