Germline Fitness-Based Scoring of Cancer Mutations
A key goal in cancer research is to find the genomic alterations that underlie malignant cells. Genomics has proved successful in identifying somatic variants at a large scale. However, it has become evident that a typical cancer exhibits a heterogenous mutation pattern across samples. Cases where t...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Genetics Society of America
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122307/ |