A method to infer positive selection from marker dynamics in an asexual population

Motivation: The observation of positive selection acting on a mutant indicates that the corresponding mutation has some form of functional relevance. Determining the fitness effects of mutations thus has relevance to many interesting biological questions. One means of identifying beneficial mutation...

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Bibliographic Details
Main Authors: Illingworth, Christopher J. R., Mustonen, Ville
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307107/