Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference
In many biological scenarios, from the development of drug resistance in pathogens to the progression of healthy cells toward cancer, quantifying the selection acting on observed mutations is a central question. One difficulty in answering this question is the complexity of the background upon which...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Genetics Society of America
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213378/ |