TREX exposes the RNA binding domain of Nxf1 to enable mRNA export
The metazoan TREX complex is recruited to mRNA during nuclear RNA processing and functions in exporting mRNA to the cytoplasm. Nxf1 is an mRNA export receptor, which binds processed mRNA and transports it through the nuclear pore complex. At present, the relationship between TREX and Nxf1 is not und...
Main Authors: | Viphakone, Nicolas, Hautbergue, Guillaume M., Walsh, Matthew, Chang, Chung-Te, Holland, Arthur, Folco, Eric G., Reed, Robin, Wilson, Stuart A. |
---|---|
Format: | Online |
Language: | English |
Published: |
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654228/ |
Similar Items
-
ORC interacts with THSC/TREX-2 and its subunits promote Nxf1 association with mRNP and mRNA export in Drosophila
by: Kopytova, Daria, et al.
Published: (2016) -
The Proteins PDIP3 and ZC11A Associate with the Human TREX Complex in an ATP-Dependent Manner and Function in mRNA Export
by: Folco, Eric G., et al.
Published: (2012) -
The role of TREX in gene expression and disease
by: Heath, Catherine G., et al.
Published: (2016) -
The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA
by: Aibara, Shintaro, et al.
Published: (2015) -
Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1
by: Zhang, Zi Chao, et al.
Published: (2011)