Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA

The mRNA export complex TREX (TREX) is known to contain Aly, UAP56, Tex1 and the THO complex, among which UAP56 is required for TREX assembly. Here, we systematically investigated the role of each human TREX component in TREX assembly and its association with the mRNA. We found that Tex1 is essentia...

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Bibliographic Details
Main Authors: Chi, Binkai, Wang, Qingliang, Wu, Guifen, Tan, Ming, Wang, Lantian, Shi, Min, Chang, Xingya, Cheng, Hong
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553972/