Luzp4 defines a new mRNA export pathway in cancer cells

Cancer testis antigens (CTAs) represented a poorly characterized group of proteins whose expression is normally restricted to testis but are frequently up-regulated in cancer cells. Here we show that one CTA, Luzp4, is an mRNA export adaptor. It associates with the TREX mRNA export complex subunit U...

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Bibliographic Details
Main Authors: Viphakone, Nicolas, Cumberbatch, Marcus G., Livingstone, Michaela J., Heath, Paul R., Dickman, Mark J., Catto, James W., Wilson, Stuart A.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344508/