An Interaction between KSHV ORF57 and UIF Provides mRNA-Adaptor Redundancy in Herpesvirus Intronless mRNA Export

The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly. Intriguingly however, depletion of Aly only leads to a modest reduction in cellular mRNA nuclear export, suggesting the existence of addit...

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Bibliographic Details
Main Authors: Jackson, Brian R., Boyne, James R., Noerenberg, Marko, Taylor, Adam, Hautbergue, Guillaume M., Walsh, Matthew J., Wheat, Rachel, Blackbourn, David J., Wilson, Stuart A., Whitehouse, Adrian
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141038/