IRSp53 Mediates Podosome Formation via VASP in NIH-Src Cells

IRSp53 Mediates Podosome Formation via VASP in NIH-Src Cells

Podosomes are cellular “feet,” characterized by F-actin-rich membrane protrusions, which drive cell migration and invasion into the extracellular matrix. Small GTPases that regulate the actin cytoskeleton, such as Cdc42 and Rac are central regulators of podosome formation. The adaptor protein IRSp53...

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Bibliographic Details
Main Authors:	Oikawa, Tsukasa, Okamura, Hitomi, Dietrich, Franziska, Senju, Yosuke, Takenawa, Tadaomi, Suetsugu, Shiro
Format:	Online
Language:	English
Published:	Public Library of Science 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608619/

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