Bayesian localisation microscopy reveals nanoscale podosome dynamics

We demonstrate a localization microscopy analysis method that is able to extract results in live cells using standard fluorescent proteins and Xenon arc lamp illumination. Our Bayesian analysis of blinking and bleaching (3B analysis) method models the entire dataset simultaneously as being generated...

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Bibliographic Details
Main Authors: Cox, Susan, Rosten, Edward, Monypenny, James, Jovanovic-Talisman, Tijana, Burnette, Dylan T., Lippincott-Schwartz, Jennifer, Jones, Gareth E., Heintzmann, Rainer
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272474/