LIN7-IRSp53: A novel pathway for filopodia and neurite formation?

Filopodia are dynamic, actin-rich finger-like structures that protrude from the cell membrane and play important roles in cell migration and neurite initiation and outgrowth. The insulin receptor substrate protein of 53 kDa (IRSp53) and the mammalian Diaphanous members of the formin family of protei...

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Bibliographic Details
Main Authors: Ferrari, Ilaria, Crespi, Arianna, Scita, Giorgio, Pietrini, Grazia
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541334/