Essential Function of Dynamin in the Invasive Properties and Actin Architecture of v-Src Induced Podosomes/Invadosomes

The large GTPase dynamin plays a key role in endocytosis but is also localized at numerous actin rich sites. We investigated dynamin functions at podosomes/invadosomes, actin-based cellular adhesion structures implicated in tissue invasion. Podosomes/invadosomes are constituted of long F-actin bundl...

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Bibliographic Details
Main Authors: Destaing, Olivier, Ferguson, Shawn M., Grichine, Alexei, Oddou, Christiane, De Camilli, Pietro, Albiges-Rizo, Corinne, Baron, Roland
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857171/