Population Genomic Scan for Candidate Signatures of Balancing Selection to Guide Antigen Characterization in Malaria Parasites

Population Genomic Scan for Candidate Signatures of Balancing Selection to Guide Antigen Characterization in Malaria Parasites

Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading to identifiable signatures of balancing selection. To comprehensively survey for genes under such selection in the human malaria parasite Plasmodium falciparum, we generated paired-end short-read sequences of para...

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Bibliographic Details
Main Authors: Amambua-Ngwa, Alfred, Tetteh, Kevin K. A., Manske, Magnus, Gomez-Escobar, Natalia, Stewart, Lindsay B., Deerhake, M. Elizabeth, Cheeseman, Ian H., Newbold, Christopher I., Holder, Anthony A., Knuepfer, Ellen, Janha, Omar, Jallow, Muminatou, Campino, Susana, MacInnis, Bronwyn, Kwiatkowski, Dominic P., Conway, David J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486833/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486833/

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