Characterization of Within-Host Plasmodium falciparum Diversity Using Next-Generation Sequence Data

Our understanding of the composition of multi-clonal malarial infections and the epidemiological factors which shape their diversity remain poorly understood. Traditionally within-host diversity has been defined in terms of the multiplicity of infection (MOI) derived by PCR-based genotyping. Massive...

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Bibliographic Details
Main Authors: Auburn, Sarah, Campino, Susana, Miotto, Olivo, Djimde, Abdoulaye A., Zongo, Issaka, Manske, Magnus, Maslen, Gareth, Mangano, Valentina, Alcock, Daniel, MacInnis, Bronwyn, Rockett, Kirk A., Clark, Taane G., Doumbo, Ogobara K., Ouédraogo, Jean Bosco, Kwiatkowski, Dominic P.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290604/