Nanog Is the Gateway to the Pluripotent Ground State
Pluripotency is generated naturally during mammalian development through formation of the epiblast, founder tissue of the embryo proper. Pluripotency can be recreated by somatic cell reprogramming. Here we present evidence that the homeodomain protein Nanog mediates acquisition of both embryonic and...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Cell Press
2009
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437554/ |