Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

Embryonic stem cell (ESC) self-renewal efficiency is determined by the level of Nanog expression. However, the mechanisms by which Nanog functions remain unclear, and in particular, direct Nanog target genes are uncharacterized. Here we investigate ESCs expressing different Nanog levels and Nanog−/−...

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Bibliographic Details
Main Authors: Festuccia, Nicola, Osorno, Rodrigo, Halbritter, Florian, Karwacki-Neisius, Violetta, Navarro, Pablo, Colby, Douglas, Wong, Frederick, Yates, Adam, Tomlinson, Simon R., Chambers, Ian
Format: Online
Language:English
Published: Cell Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473361/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473361/

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