Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells

Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells

B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B13, since they are made by bioisosterically substituting the...

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Bibliographic Details
Main Authors:	Lee, Seul Ki Chan, Park, Sang Min, Im, Chaeuk
Format:	Online
Language:	English
Published:	The Korean Physiological Society and The Korean Society of Pharmacology 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282231/

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