Searching for DNA Lesions:
Structural Evidence for
Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine
DNA Glycosylase

Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase

Bibliographic Details
Main Authors:	Setser, Jeremy W., Lingaraju, Gondichatnahalli M., Davis, C. Ainsley, Samson, Leona D., Drennan, Catherine L.
Format:	Online
Language:	English
Published:	American Chemical Society 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254189/

Similar Items

Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA*
by: Lingaraju, Gondichatnahalli M., et al.
Published: (2011)

Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA
by: Morgan, Michael T., et al.
Published: (2011)

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA
by: Malik, Shuja S., et al.
Published: (2015)

Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging
by: Buechner, Claudia N., et al.
Published: (2015)

DNA glycosylases: in DNA repair and beyond
by: Jacobs, Angelika L., et al.
Published: (2011)

Electrostatic Properties of Complexes along a DNA Glycosylase Damage Search Pathway
by: Cravens, Shannen L., et al.
Published: (2014)

8-Oxoguanine DNA Glycosylases: One Lesion, Three Subfamilies
by: Faucher, Frédérick, et al.
Published: (2012)

A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine–DNA glycosylase
by: Li, Haoquan, et al.
Published: (2016)

Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA
by: Zhang, Liang, et al.
Published: (2012)

MUTYH DNA glycosylase: the rationale for removing undamaged bases from the DNA
by: Markkanen, Enni, et al.
Published: (2013)

Thermodynamics of the DNA Damage Repair Steps of Human 8-Oxoguanine DNA Glycosylase
by: Kuznetsov, Nikita A., et al.
Published: (2014)

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation
by: Schomacher, Lars, et al.
Published: (2016)

Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase
by: Schormann, Norbert, et al.
Published: (2015)

A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily
by: Sang, Pau Biak, et al.
Published: (2015)

5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases
by: Le Bihan, Yann-Vaï, et al.
Published: (2011)

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury
by: Yu, Amy Marie, et al.
Published: (2016)

Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
by: Kachhap, Sushant, et al.
Published: (2004)

The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation
by: Ba, Xueqing, et al.
Published: (2014)

Thermodynamics of the multi-stage DNA lesion recognition and repair by formamidopyrimidine-DNA glycosylase using pyrrolocytosine fluorescence—stopped-flow pre-steady-state kinetics
by: Kuznetsov, Nikita A., et al.
Published: (2012)

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
by: Calvo, Jennifer A., et al.
Published: (2013)

Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase
by: Kuznetsov, Nikita A., et al.
Published: (2005)

The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage
by: Shikazono, Naoya, et al.
Published: (2006)

Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
by: Schormann, Norbert, et al.
Published: (2007)

Functional Characterization of 8-Oxoguanine DNA Glycosylase of Trypanosoma cruzi
by: Furtado, Carolina, et al.
Published: (2012)

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase
by: Cole, Ambrose R., et al.
Published: (2013)

Demethylation initiated by ROS1 glycosylase involves random sliding along DNA
by: Ponferrada-Marín, María Isabel, et al.
Published: (2012)

A Mutant of Uracil DNA Glycosylase That Distinguishes between Cytosine and 5-Methylcytosine
by: Kimber, Scott T., et al.
Published: (2014)

5-Methylcytosine Recognition by Arabidopsis thaliana DNA Glycosylases DEMETER and DML3
by: Brooks, Sonja C., et al.
Published: (2014)

Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor
by: Wang, Hao-Ching, et al.
Published: (2014)

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs
by: Jacobs, Aaron C., et al.
Published: (2013)

Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase
by: Schormann, N., et al.
Published: (2013)

Expression and the Peculiar Enzymatic Behavior of the Trypanosoma cruzi NTH1 DNA Glycosylase
by: Ormeño, Fernando, et al.
Published: (2016)

Cadmium(II) inhibition of human uracil-DNA glycosylase by catalytic water supplantation
by: Gokey, Trevor, et al.
Published: (2016)

Molecular crowding enhances facilitated diffusion of two human DNA glycosylases
by: Cravens, Shannen L., et al.
Published: (2015)

Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA
by: Dunn, Andrew R., et al.
Published: (2011)

Defective Repair of Oxidative Base Lesions by the DNA Glycosylase Nth1 Associates with Multiple Telomere Defects
by: Vallabhaneni, Haritha, et al.
Published: (2013)

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures
by: Zhou, Jia, et al.
Published: (2015)

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures
by: Zhou, Jia, et al.
Published: (2015)

A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA
by: Ushijima, Yasuhiro, et al.
Published: (2005)

Formamidopyrimidine-DNA glycosylase enhances arsenic-induced DNA strand breaks in PHA-stimulated and unstimulated human lymphocytes.
by: Li, D, et al.
Published: (2001)