Alkylation induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins

by Bugni, James M., Meira, Lisiane B., Samson, Leona D.
Published 2008

Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase

by Setser, Jeremy W., Lingaraju, Gondichatnahalli M., Davis, C. Ainsley, Samson, Leona D., Drennan, Catherine L.
Published 2011

Identification of Novel Human Damage Response Proteins Targeted through Yeast Orthology

by Svensson, J. Peter, Fry, Rebecca C., Wang, Emma, Somoza, Luis A., Samson, Leona D.
Published 2012

Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA*

by Lingaraju, Gondichatnahalli M., Davis, C. Ainsley, Setser, Jeremy W., Samson, Leona D., Drennan, Catherine L.
Published 2011

Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

by Mazumder, Aprotim, Pesudo, Laia Quiros, McRee, Siobhan, Bathe, Mark, Samson, Leona D.
Published 2013

Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response

by Beharry, Andrew A., Nagel, Zachary D., Samson, Leona D., Kool, Eric T.
Published 2016

The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury

by Yu, Amy Marie, Calvo, Jennifer A., Muthupalani, Suresh, Samson, Leona D.
Published 2016

Transcriptional Networks in S. cerevisiae Linked to an Accumulation of Base Excision Repair Intermediates

by Rusyn, Ivan, Fry, Rebecca C., Begley, Thomas J., Klapacz, Joanna, Svensson, J. Peter, Ambrose, Mark, Samson, Leona D.
Published 2007

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA

by Fry, Rebecca C, DeMott, Michael S, Cosgrove, Joseph P, Begley, Thomas J, Samson, Leona D, Dedon, Peter C
Published 2006

Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance

by Svensson, J Peter, Pesudo, Laia Quirós, Fry, Rebecca C, Adeleye, Yeyejide A, Carmichael, Paul, Samson, Leona D
Published 2011

Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress

by Tentner, Andrea R, Lee, Michael J, Ostheimer, Gerry J, Samson, Leona D, Lauffenburger, Douglas A, Yaffe, Michael B
Published 2012

Genomic Phenotyping by Barcode Sequencing Broadly Distinguishes between Alkylating Agents, Oxidizing Agents, and Non-Genotoxic Agents, and Reveals a Role for Aromatic Amino Acids i...

by Svensson, J. Peter, Quirós Pesudo, Laia, McRee, Siobhan K., Adeleye, Yeyejide, Carmichael, Paul, Samson, Leona D.
Published 2013

Activation of Inflammation/NF-κB Signaling in Infants Born to Arsenic-Exposed Mothers

by Fry, Rebecca C, Navasumrit, Panida, Valiathan, Chandni, Svensson, J. Peter, Hogan, Bradley J, Luo, Manlin, Bhattacharya, Sanchita, Kandjanapa, Krittinee, Soontararuks, Sumitra, Nookabkaew, Sumontha, Mahidol, Chulabhorn, Ruchirawat, Mathuros, Samson, Leona D
Published 2007

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1

by Calvo, Jennifer A., Moroski-Erkul, Catherine A., Lake, Annabelle, Eichinger, Lindsey W., Shah, Dharini, Jhun, Iny, Limsirichai, Prajit, Bronson, Roderick T., Christiani, David C., Meira, Lisiane B., Samson, Leona D.
Published 2013

Integrated Molecular Analysis Indicates Undetectable Change in DNA Damage in Mice after Continuous Irradiation at ~ 400-fold Natural Background Radiation

by Olipitz, Werner, Wiktor-Brown, Dominika, Shuga, Joe, Pang, Bo, McFaline, Jose, Lonkar, Pallavi, Thomas, Aline, Mutamba, James T, Greenberger, Joel S, Samson, Leona D, Dedon, Peter C, Yanch, Jacquelyn C, Engelward, Bevin P
Published 2012

The Cycad Genotoxin MAM Modulates Brain Cellular Pathways Involved in Neurodegenerative Disease and Cancer in a DNA Damage-Linked Manner

by Kisby, Glen E., Fry, Rebecca C., Lasarev, Michael R., Bammler, Theodor K., Beyer, Richard P., Churchwell, Mona, Doerge, Daniel R., Meira, Lisiane B., Palmer, Valerie S., Ramos-Crawford, Ana-Luiza, Ren, Xuefeng, Sullivan, Robert C., Kavanagh, Terrance J., Samson, Leona D., Zarbl, Helmut, Spencer, Peter S.
Published 2011