Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

Thymine DNA Glycosylase (TDG) performs essential functions in maintaining genetic integrity and epigenetic regulation. Initiating base excision repair, TDG removes thymine from mutagenic G·T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymeth...

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Bibliographic Details
Main Authors: Malik, Shuja S., Coey, Christopher T., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627079/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627079/

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