Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor
Cholesterol influences ion-channel function, distribution and clustering in the membrane, endocytosis, and exocytic sorting of the nicotinic acetylcholine receptor (AChR). We report the occurrence of a cholesterol recognition motif, here coined “CARC”, in the transmembrane regions of AChR subunits t...
Main Authors: | Baier, Carlos J., Fantini, Jacques, Barrantes, Francisco J. |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216556/ |
Similar Items
-
Transient Cholesterol Effects on Nicotinic Acetylcholine Receptor Cell-Surface Mobility
by: Almarza, Gonzalo, et al.
Published: (2014) -
Cell-surface translational dynamics of nicotinic acetylcholine receptors
by: Barrantes, Francisco J.
Published: (2014) -
How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains
by: Fantini, Jacques, et al.
Published: (2013) -
Mechanics of Channel Gating of the Nicotinic Acetylcholine Receptor
by: Liu, Xinli, et al.
Published: (2008) -
Nicotinic Receptor Fourth Transmembrane Domain: Hydrogen Bonding by Conserved Threonine Contributes to Channel Gating Kinetics
by: Bouzat, Cecilia, et al.
Published: (2000)