Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor
Cholesterol influences ion-channel function, distribution and clustering in the membrane, endocytosis, and exocytic sorting of the nicotinic acetylcholine receptor (AChR). We report the occurrence of a cholesterol recognition motif, here coined “CARC”, in the transmembrane regions of AChR subunits t...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216556/ |