Layer-Specific Modulation of the Prefrontal Cortex by Nicotinic Acetylcholine Receptors

Acetylcholine signaling through nicotinic receptors (nAChRs) in the prefrontal cortex (PFC) is crucial for attention. Nicotinic AChRs are expressed on glutamatergic inputs to layer V (LV) cells and on LV interneurons and LVI pyramidal neurons. Whether PFC layers are activated by nAChRs to a similar...

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Bibliographic Details
Main Authors: Poorthuis, Rogier B., Bloem, Bernard, Schak, Benita, Wester, Jordi, de Kock, Christiaan P. J., Mansvelder, Huibert D.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513956/