The role of the precursor structure in the biogenesis of microRNA
The human genome contains more than 1,000 microRNA (miRNA) genes, which are transcribed mainly by RNA polymerase II. The canonical pathway of miRNA biogenesis includes the nuclear processing of primary transcripts (pri-miRNAs) by the ribonuclease Drosha and further cytoplasmic processing of pre-miRN...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
SP Birkhäuser Verlag Basel
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155042/ |