In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats
Polyglutamine diseases, including Huntington’s disease and a number of spinocerebellar ataxias, are caused by expanded CAG repeats that are located in translated sequences of individual, functionally-unrelated genes. Only mutant proteins containing polyglutamine expansions have long been thought to...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581269/ |