Real-time in vivo imaging of p16Ink4a reveals cross talk with p53

Real-time in vivo imaging of p16Ink4a reveals cross talk with p53

Expression of the p16Ink4a tumor suppressor gene, a sensor of oncogenic stress, is up-regulated by a variety of potentially oncogenic stimuli in cultured primary cells. However, because p16Ink4a expression is also induced by tissue culture stress, physiological mechanisms regulating p16Ink4a express...

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Bibliographic Details
Main Authors: Yamakoshi, Kimi, Takahashi, Akiko, Hirota, Fumiko, Nakayama, Rika, Ishimaru, Naozumi, Kubo, Yoshiaki, Mann, David J., Ohmura, Masako, Hirao, Atsushi, Saya, Hideyuki, Arase, Seiji, Hayashi, Yoshio, Nakao, Kazuki, Matsumoto, Mitsuru, Ohtani, Naoko, Hara, Eiji
Format: Online
Language:English
Published: The Rockefeller University Press 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728398/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728398/

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