Irreversibility of cellular senescence: dual roles of p16INK4a/Rb-pathway in cell cycle control

by Takahashi, Akiko, Ohtani, Naoko, Hara, Eiji
Published 2007

The long-term consequences of hybridization between the two Daphnia species, D. galeata and D. dentifera, in mature habitats

by Ishida, Seiji, Takahashi, Akiko, Matsushima, Noe, Yokoyama, Jun, Makino, Wataru, Urabe, Jotaro, Kawata, Masakado
Published 2011

Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53

by Maehara, Kayoko, Yamakoshi, Kimi, Ohtani, Naoko, Kubo, Yoshiaki, Takahashi, Akiko, Arase, Seiji, Jones, Nic, Hara, Eiji
Published 2005

E2FBP1 antagonizes the p16INK4A-Rb tumor suppressor machinery for growth suppression and cellular senescence by regulating promyelocytic leukemia protein stability

by Fukuyo, Yayoi, Takahashi, Akiko, Hara, Eiji, Horikoshi, Nobuo, Pandita, Tej K, Nakajima, Takuma
Published 2011

Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism

by Higashino, Fumihiro, Aoyagi, Mariko, Takahashi, Akiko, Ishino, Masaho, Taoka, Masato, Isobe, Toshiaki, Kobayashi, Masanobu, Totsuka, Yasunori, Kohgo, Takao, Shindoh, Masanobu
Published 2005

Real-time in vivo imaging of p16Ink4a reveals cross talk with p53

by Yamakoshi, Kimi, Takahashi, Akiko, Hirota, Fumiko, Nakayama, Rika, Ishimaru, Naozumi, Kubo, Yoshiaki, Mann, David J., Ohmura, Masako, Hirao, Atsushi, Saya, Hideyuki, Arase, Seiji, Hayashi, Yoshio, Nakao, Kazuki, Matsumoto, Mitsuru, Ohtani, Naoko, Hara, Eiji
Published 2009

Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growth

by Takahashi, Akiko, Ishii, Genichiro, Neri, Shinya, Yoshida, Tatsuya, Hashimoto, Hiroko, Suzuki, Shigeki, Umemura, Shigeki, Matsumoto, Shingo, Yoh, Kiyotaka, Niho, Seiji, Goto, Koichi, Ohmatsu, Hironobu, Nagai, Kanji, Gemma, Akihiko, Ohe, Yuichiro, Ochiai, Atsushi
Published 2015

Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice

by Sato, Seidai, Kawamata, Yuka, Takahashi, Akiko, Imai, Yoshinori, Hanyu, Aki, Okuma, Atsushi, Takasugi, Masaki, Yamakoshi, Kimi, Sorimachi, Hiroyuki, Kanda, Hiroaki, Ishikawa, Yuichi, Sone, Saburo, Nishioka, Yasuhiko, Ohtani, Naoko, Hara, Eiji
Published 2015

NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy

by Kawano, Mitsuko, Nakayama, Masafumi, Aoshima, Yusuke, Nakamura, Kyohei, Ono, Mizuho, Nishiya, Tadashi, Nakamura, Syou, Takeda, Yuri, Dobashi, Akira, Takahashi, Akiko, Endo, Misato, Ito, Akiyo, Ueda, Kyosuke, Sato, Naoki, Higuchi, Shigehito, Kondo, Takeru, Hashimoto, Suguru, Watanabe, Masamichi, Watanabe, Makoto, Takahashi, Tetsu, Sasaki, Keiichi, Nakamura, Masanori, Sasazuki, Takehiko, Narushima, Takayuki, Suzuki, Ryuji, Ogasawara, Kouetsu
Published 2014

Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis

by Umemura, Shigeki, Mimaki, Sachiyo, Makinoshima, Hideki, Tada, Satoshi, Ishii, Genichiro, Ohmatsu, Hironobu, Niho, Seiji, Yoh, Kiyotaka, Matsumoto, Shingo, Takahashi, Akiko, Morise, Masahiro, Nakamura, Yuka, Ochiai, Atsushi, Nagai, Kanji, Iwakawa, Reika, Kohno, Takashi, Yokota, Jun, Ohe, Yuichiro, Esumi, Hiroyasu, Tsuchihara, Katsuya, Goto, Koichi
Published 2014