Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo
Monocytes can develop into dendritic cells (DCs) that migrate to lymph nodes (LNs) and present antigens to T cells. However, we find that this differentiation is blocked when monocytes accumulate subcutaneously in response to bacteria or lipopolysaccharide (LPS). The inhibition of DC differentiation...
Main Authors: | Rotta, Gianluca, Edwards, Emmerson W., Sangaletti, Sabina, Bennett, Clare, Ronzoni, Simona, Colombo, Mario P., Steinman, Ralph M., Randolph, Gwendalyn J., Rescigno, Maria |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2003
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194237/ |
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