APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection

HIV-1 infects immature dendritic cells (iDCs), but infection is inefficient compared with activated CD4+ T cells and only involves a small subset of iDCs. We analyzed whether this could be attributed to specific cellular restrictions during the viral life cycle. To study env-independent restriction...

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Bibliographic Details
Main Authors: Pion, Marjorie, Granelli-Piperno, Angela, Mangeat, Bastien, Stalder, Romaine, Correa, Rafael, Steinman, Ralph M., Piguet, Vincent
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118170/